Two new antiinflammatory elemanolides from Centaurea chilensis.

نویسندگان

  • R E Negrete
  • N Backhouse
  • I Cajigal
  • C Delporte
  • B K Cassels
  • E Breitmaier
  • G Eckhardt
چکیده

Two previously undescribed elemanolide esters, the 2-methylpropanoate and 2-methyl-2-propenoate of 11,13-dehydromelitensin, were isolated in the course of a bioassay-guided fractionation from the aerial parts of Centaurea chilensis Hook. et Arn., used traditionally to treat 'gout and rheumatism'. The mixture of both substances exhibits anti-inflammatory activity in the carrageenan-induced paw edema assay.

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عنوان ژورنال:
  • Journal of ethnopharmacology

دوره 40 3  شماره 

صفحات  -

تاریخ انتشار 1993